Schiff Bases Derived From Isonitrosoacetophenone and 2,4 Dithiobiurets: Application In Environment

Mayuri R. Joshi

Vol 10, Special Issue 2024

Page Number: 076-080

Abstract:

Applications of Schiff bases chelating compounds in wider quantitative analysis and sample preparations for chemical analysis have been reviewed .The synthesis and stability of Schiff bases chelates have been discussed in this paper. The wider applications in analytical field and latest applications of Schiff bases in green technology are found in progress. The metal complexes have been screened for their antibacterial activity. Escherichia Coli, Staphylococcus, Bacillus Cereus, Bacillus Subtilis were studied on laboratory grown cultures, these yield several kinds of information which are of value in guiding and understanding their therapeutic use. The work reported here deals with the synthesis and spectroscopic studies of some transition metal complexes with poly dentate Schiff bases. These Schiff bases were derived by condensing carbonyl oximes-like isonitrosoacetophenone, α-benzyl monoxime, isonitroso acetyl acetone with amines like 2,4 dithiobiurets. The characterization of the complexes was done on the basis of elemental analysis, molar conductivity, spectral IR, electronic thermal analysis spectra. The metal complexes have been screened for their antimicrobial activity. The concentration required to inhibit various organisms and the effects of environmental conditions on their activity are of paramount importance. The complexes show moderate activity against (10-22 mm) the above mentioned bacteria. This shows that besides the complex formation, the nature of the metal ion has important role in the inhibition of the pathogenic activity of the bacteria. The conductivity measurement indicates that they are non-electrolyte in nature. The complexes are thermally stable, insoluble in water but soluble in organic solvent to varying extent .The room temperature magnetic susceptibility measurements indicate their octahedral geometry which is further supported by electronic absorption /diffuse reflectance spectra.

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